In this section, you’ll find a variety of resources to help you better understand Optune Gio, share this novel treatment with your patients who have newly diagnosed or recurrent glioblastoma (GBM), and start prescribing Optune Gio.

Print Resources

Optune Gio CVA

Learn about Optune Gio + temozolomide (TMZ) for patients with newly diagnosed GBM.

MyNovocureTM Brochure

See the MyNovocure brochure for more information and patient support to learn how nCompass supports patients at every step of their journey.

Optune Gio for Elderly Patients

Learn about Optune Gio + TMZ in elderly patients with histologically confirmed, newly diagnosed GBM.

Management Guidelines for Dermatologic Adverse Events (dAEs) Brochure

This brochure provides guidance to you and your practice for identifying, preventing, and managing dAEs for Optune Gio users.

Understanding Optune Gio: Patient Education Program Flyer

Learn how you can participate in the Understanding Optune Gio: Patient Education Program to get the support you need through educational sessions with a Novocure representative.

Optune Gio for Biopsy-Only Patients

Learn about Optune Gio + TMZ in biopsy-only patients.

Print Resources for Patients

Optune Gio Patient Brochure

Provides a high-level overview of Optune Gio, including clinical efficacy, how to obtain and properly use Optune Gio, and the MyNovocure Support Program.

MyNovocure Patient Brochure

An in-depth look at nCompass from the first welcome call to ongoing support and education throughout treatment.

MyLinkTM Quick Reference Card

Introduces patients to the MyLink hardware and provides a step-by-step guide of how to use it.

Patient Scalp Care Guidelines

Answers your patients’ questions about scalp care and transducer array placement.

Optune Gio Troubleshooting Tips

A guide for patients and caregivers to refer to when the Optune Gio device alarm goes off to easily determine and address the cause.

Patient Travel Support by MyNovocure Brochure

Answers frequently asked questions about travel and provides checklists of what to pack and bring when traveling with Optune Gio.

Additional Resources

Peer-Reviewed Publications

Review various publications about Optune Gio

Calendar of Events

Optune Gio open houses and events focused on brain cancer

See publicationsSee upcoming events

Indications For Use


Optune GioTM is intended as a treatment for adult patients (22 years of age or older) with histologically confirmed glioblastoma multiforme (GBM).


Optune Gio with temozolomide is indicated for the treatment of adult patients with newly diagnosed, supratentorial glioblastoma following maximal debulking surgery, and completion of radiation therapy together with concomitant standard of care chemotherapy.


For the treatment of recurrent GBM, Optune Gio is indicated following histologically or radiologically confirmed recurrence in the supratentorial region of the brain after receiving chemotherapy. The device is intended to be used as a monotherapy and is intended as an alternative to standard medical therapy for GBM after surgical and radiation options have been exhausted.

Important Safety Information



Do not use Optune Gio in patients with an active implanted medical device, a skull defect (such as, missing bone with no replacement), or bullet fragments. Use of Optune Gio together with implanted electronic devices has not been tested and may theoretically lead to malfunctioning of the implanted device. Use of Optune Gio together with skull defects or bullet fragments has not been tested and may possibly lead to tissue damage or render Optune Gio ineffective.


Do not use Optune Gio in patients that are known to be sensitive to conductive hydrogels. In this case, skin contact with the gel used with Optune Gio may commonly cause increased redness and itching, and rarely may even lead to severe allergic reactions such as shock and respiratory failure.


Warnings and precautions


Optune Gio can only be prescribed by a healthcare provider that has completed the required certification training provided by Novocure (the device manufacturer).


Do not prescribe Optune Gio for patients that are pregnant, you think might be pregnant or are trying to get pregnant, as the safety and effectiveness of Optune Gio in these populations have not been established.


The most common (≥10%) adverse events involving Optune Gio in combination with temozolomide were thrombocytopenia, nausea, constipation, vomiting, fatigue, medical device site reaction, headache, convulsions, and depression.


The most common (≥10%) adverse events seen with Optune Gio monotherapy were medical device site reaction and headache.
The following adverse reactions were considered related to Optune Gio when used as monotherapy: medical device site reaction, headache, malaise, muscle twitching, fall, and skin ulcer.


Use of Optune Gio in patients with an inactive implanted medical device in the brain has not been studied for safety and effectiveness, and use of Optune Gio in these patients could lead to tissue damage or lower the chance of Optune Gio being effective.


If the patient has an underlying serious skin condition on the scalp, evaluate whether this may prevent or temporarily interfere with Optune Gio treatment.


Please click here to see the Optune GioTM Instructions For Use for complete information regarding the device's indications, contraindications, warnings, and precautions.

Novocure Websites

This website is intended for people seeking information on Optune Gio.

On this site, videos and images identified as Optune Gio users, caregivers, or healthcare professionals depict actual patients, caregivers, and healthcare professionals.

Patient images reflect the health status of the patients at the time each photo or video was taken.


©2023 Novocure GmbH. All Rights Reserved. 

Optune, Optune Gio, MyNovocure, NovoTAL, and Novocure are trademarks of Novocure GmbH. 

All other trademarks, registered or unregistered, are the property of their respective owners. 

US-OPG-00197v1.0 November 2023